| Date | Opponent | Location | Time/Result |
| Fri., Nov. 22 | @University of Richmond | Richmond, Va. | 7:30 p.m. |
| Sun., Nov.24 | @William & Mary | Williamsburg, Va. | 2:00 p.m. |
| Tues., Nov. 26 | Howard University | RADFORD | 7:00 p.m. |
| Sat., Nov. 30 | North Carolina A&T | RADFORD | 7:00 p.m. |
| Tue., Dec. 3 | East Carolina University | RADFORD | 7:00 p.m. |
| Fri., Dec. 6 | @American University | Washington, D.C. | 7:00 p.m. |
| Sat., Dec. 14 | @Marshall University | Huntington, W.Va. | 7:30 p.m. |
| Sat., Dec. 21 | @University of Akron | Arkron, Ohio | 3:00 p.m. |
| Mon., Dec. 23 | @The Ohio State University (Espn Plus) |
Columbus, Ohio | 8:00 p.m. |
| Fri., Dec 27 | vs. Duquesne University # | Miami, Fla. | 6:00 p.m. |
| Sat., Dec. 28 | Florida International/St. Francis (NY) # | Miami, Fla. | TBA |
| Thrus., Jan. 2 | Winthrop University * | RADFORD | 8:00 p.m. |
| Sat., Jan 4 | High Point University * | RADFORD | 7:00 p.m. |
| Wed., Jan 8 | @Birmingham Southern University | Birmingham, Ala. | 7:00 p.m. (CST) |
| Sat., Jan. 11 | UNC Asheville * | RADFORD | 7:00 p.m. |
| Sat., Jan. 18 | @Liberty University * | Lynchburg, Va. | 7:00 p.m. |
| Mon., Jan. 20 | @Coastal Carolina University * | Conway, S.C. | 7:00 p.m. |
| Sat., Jan. 25 | @Charleston Southern University * | Charleston, S.C. | 4:00 p.m. |
| Wed., Jan. 29 | Elon University | RADFORD | 7:00 p.m. |
| Sun., Feb 2 | @High Point University * | High Point, N.C. | 4:00 p.m. |
| Wed., Feb 5 | @Winthrop University * | Rock Hill, S.C. | 7:00 p.m. |
| Thurs., Feb 13 | @UNC Asheville * | Asheville, N.C. | 7:00 p.m. |
| Sat. Feb., 15 | Coastal Carolina University * | RADFORD | 7:00 p.m. |
| Mon., Feb. 17 | Charleston Southern University * | RADFORD | 7:00 p.m. |
| Sat., Feb 22 | @Elon University * | Elon, N.C. | 7:00 p.m. |
| Mon., Feb. 24 | Birmingham Southern College | RADFORD | 7:00 p.m. |
| Fri., Feb. 28 | Liberty University * (HTS) | RADFORD | 7:00 p.m. |
| Tues., Mar. 4 | Big South Conference Tournament First Round ^ |
@Higher Seed | 7:00 p.m. |
| Fri., Mar. 7 | Big South Conference Semi-Finals % (Comcast South) |
Lynchburg, Va. | TBA |
| Sat., Mar. 8 | Big South Championship % (ESPN2) |
Lynchburg, Va. | TBA |
| * Big South Conference games. # Florida International New Year's Classic, Miami, Fla. ^ At Higher Seed % BSC Tournament, Liberty University, Lynchburg, Va. |
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